Integrated single-cell and bulk RNA sequencing reveals CREM is involved in the pathogenesis of ulcerative colitis

Background: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by persistent colonic inflammation.Here, we performed a systematic analysis to gain better insights into UC 310.32.42.50.01.001 pathogenesis.Methods: We analyzed two UC-related datasets extracted from the gene expression omnibus database using several bioinformatics

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Supervised Learning to Predict Sperm Sorting by Magnetophoresis

Machine learning is gaining popularity in the commercial world, but its benefits are yet to be well-utilised by many in the microfluidics community.There is immense potential in bridging the gap between applied engineering and artificial intelligence as well as statistics.We illustrate this by a case study investigating the sorting of sperm cells f

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SPRY4-AS1, A Novel Enhancer RNA, Is a Potential Novel Prognostic Biomarker and Therapeutic Target for Hepatocellular Carcinoma

A growing number of evidence have demonstrated the involvement of enhancer RNAs (eRNAs) in tumor progression.However, the possible functions of eRNAs in hepatocellular carcinoma (HCC) remain largely unclear.Our present research aimed to screen critical eRNAs and to further delve into the clinical significance of eRNAs in HCC patients.In this study,

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